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haematologica | 2018; 103(6)
Cytokines increase AML but not MDS engraftment
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Figure 6. Myelodysplastic syndrome-initiating cells can be maintained in NSG-S mice. (A) Schematic representation of experimental set up for secondary intrafemoral transplanta- tions. (Β) Percentages of hCD45+ cells at 13 weeks after transplantation. Characteristic gat- ing strategy for analyzing the (C) myeloid (CD33), lymphoid (CD19, CD3), progenitor (CD45RA, CD123, CD38) and (D) erythroid (GlyA) subpopulations found in the bone marrow of mice engrafted with hCD45+ cells isolated from primary mice.
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