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Multicenter validation of targeted NGS in CLL
Figure 2. Pairwise comparison of mutations detected by centers utilizing the Multiplicom, Illumina TSCA and HaloPlex assays. Mutation plots depicting the concor- dance and accuracy (narrow range) of the variant allele frequency (VAF) of variants found in this study. Variants are listed on the y-axis and variants detected by each center are denoted by different shapes. The VAF scale is on the x-axis and a VAF difference of less than 10% between partner centers is denoted by black shapes while red shapes indicate a VAF difference of greater than 10% between partner centers.
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