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Case Report
therefore be rapidly progressive, underlining the impor- tance of recognizing SRC-related thrombocytopenia among the other forms of inherited thrombocytopenia. In conclusion, the investigation of this patient provides novel information on the pathogenetic and clinical fea- tures of SRC-related thrombocytopenia and on the func- tions of SRC in human Mk.
Serena Barozzi,1* Christian A. Di Buduo,2,3* Caterina Marconi,4 Valeria Bozzi,1 Marco Seri,4 Francesca Romano,5 Alessandra Balduini2,3
and Alessandro Pecci1
1Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia; 2Department of Molecular Medicine, University of Pavia, Pavia; 3Laboratory of Biochemistry, Biotechnology and Advanced Diagnosis, IRCCS Policlinico San Matteo Foundation, Pavia; 4Department of Medical and Surgical Sciences, University of Bologna, Bologna and 5Postgraduate School of Pediatrics, University of Torino, Torino, Italy
*SB and CADB contributed equally as co-first authors. Correspondence:
ALESSANDRO PECCI - alessandro.pecci@unipv.it doi:10.3324/haematol.2020.268516
Disclosures: no conflicts of interest to disclose.
Contributions: SB and CADB performed research, analyzed and interpreted the laboratory data, wrote the manuscript; CM,VB, MS, performed research and analyzed and interpreted the laboratory data; FR collected and interpreted the clinical data; AB analyzed and inter- preted the laboratory data and wrote the manuscript; AP designed research, analyzed and interpreted the data, and wrote the manuscript. All the authors critically revised the manuscript and approved the final version.
Acknowledgments: the authors would like to thank the patient
and his family, and Dr. Emanuela Boveri, Dept. of Human Pathology, IRCCS Policlinico San Matteo Foundation, for helpful discussion on bone marrow histological findings.
Funding: This study has been supported by the Telethon Foundation (grant no. GGP17106, to AP); the IRCCS Policlinico San Matteo Foundation (to AP); the European Union (H2020-Project ID 767309, to AB); the Italian Ministry of Health (GR-2018-12367235, to CADB).
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