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Letters to the Editor
EFS
A
B
D
PFS
C
E
OS
F
Figure 2. Comparison of double hit in double expressor and non-double expressor (DE). (A-C) Within the DE group, the occurrence of a genetic double hit for MYC and BCL-2 (n=8 of 32, 25%) failed to confer a significant prognostic difference in EFS (P=0.628), PFS (P=0.375) and OS (P=0.059) between patients with DH positive and DH negative tumors. (D-F) Within the non DE group, the occurrence of a genetic double hit for MYC and BCL-2 (n=11 of 354, 3%) failed to confer a significant prognostic difference in EFS (P=0.099) and OS (P=0.222) between patients with DH positive and DH negative tumors.
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