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Letters to the Editor
EFS
A
B
PFS
C
D
F
E
Figure 1. Event-free survival (EFS), progression-free survival (PFS) and overall survival (OS) of patients stratified according to Myc and BCL-2 expression. (A-C) The double expressor (DE) subgroup had a significant inferior clinical course, while the double negative (DN) subset had a superior outcome and the MYC-/BCL- 2+ subset had an intermediate prognosis, with the differences being statistically significant for EFS, PFS and OS. (D-F) The cases were stratified according to MYC protein expression only, patients with MYC >70% experienced inferior outcome in EFS (P=0.005), PFS (P=0.004) and OS (P=0.002) in comparison to patients with low MYC expression (<40%). No difference in prognosis was seen between patients whose tumors had MYC expression <40% and 40-70%.
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OS