Page 47 - Haematologica Atlas of Hematologic Cytology

CHAPTER 5 - Parasitic and fungal diseases
Figure 3 Plasmodium ovale ovale ovale in in in in in a a a a a a a a a a a a a a a thin or or or or thick (E) blood smear (A) RBC containing a a a a a a a a a a a a a a a P P P ovale ovale ovale ring-form trophozoite trophozoite P P P ovale ovale ovale trophozoites are are dis nguished by by a a a a a a a a a a a a a a a a a a a a a a a strong and and solid cytoplasm Infected cells may may be be normal or or or or or slightly enlar- ged in in in in size and and and are are rounded or or or oval-shaped Schu Schu ner ner s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s s ppling may may be be evidenced by by by Giemsa staining Note the the the the oval oval oval oval oval shape shape shape of of the the the the the RBC RBC and and and the the the the the Schu Schu ner ner s s s s s s s s s s s s s s s s s s s ne ne ne dots (B) RBC RBC parasi zed by by a a a a a a a a a a a a a a a a a a a a a a P P ovale ovale trophozoite trophozoite As they develop P P ovale ovale trophozoites acquire a a a a a a a a a a a a a a a a a a a sturdy cytoplasm losing any ring shape shape shape and and their morphology resembles more closely that of of of of gametocytes Note Note the the the the the the the ne ne Schu ner s s s s s s s s s s s s s s s s s s s s s s s s s s s s ppling the the the the the the the double double large chroma chroma n n n n n n n n n n n n n dot dot of of of the the the the the the the trophozoite trophozoite trophozoite the the the the the the the oval oval shape shape of of of the the the the the the the the the the RBC RBC RBC RBC and and its mbriated surface (C) RBC RBC RBC RBC containing a a a a a a a a a a a a a a a a a a a a a a mature mature P P ovale ovale trophozoite trophozoite Note Note the the the the the the the the the the double double chroma chroma n n n n n n n n n n n n dot dot the the the the the the the the compact cytoplasm of the the the the the the the the parasite and and the the the the the the the the vacuole inside the the the the the the the the RBC RBC RBC RBC RBC (D) RBC RBC RBC RBC RBC infected by a a a a a a a a a a a a a a a a a a a a a a mature mature P P ovale ovale tropho- zoite zoite zoite Note Note the the the the the the ne ne ne ne Schu ner s s s s s s s s s s s s s s s dots Note Note also the the the the the the upper RBC RBC RBC containing a a a a a a a a a a a a a a a a a a a a ring-form trophozoite with a a a a a a a a a a a a a a a a a a a a ne ne ne ne shar- ply-de ned cytoplasm (E) P P ovale ovale schizont schizont in in in in a a a a a a a a a a a a a a a a a a a a a thick blood smear composed of six merozoites merozoites P P ovale ovale schizonts are are characterized by by from 6 to to to up to to to 14 merozoites merozoites They usually show large large nuclei nuclei and are are located around a a a a a a a a a a a a a a a a a a a a a dark-brown pigment pigment mass Note Note Note the the the the the rela vely large large nuclei nuclei (F) RBC RBC infected infected by by a a a a a a a a a a a a a a a a a a a a a a a a a P P ovale ovale schizont schizont Note Note Note the the the the the brown brown pigment pigment inside the the the the the the the the parasite and and the the the the the the the the slightly amoeboid appearance of of of the the the the the the the the infected infected infected red cell cell (G) RBC RBC RBC containing containing a a a a a a a a a a a a a a a a a a a a a P P P ovale ovale ovale schizont schizont Note Note Note the the the the the the the the the higher number of of of of merozoites and and and the the the the the the the the the oval oval oval shape of of of of the the the the the the the the the infected infected infected cell cell cell (H) RBC RBC containing containing P P ovale ovale microgametocyte Dis nc ve features are the the the the the the the the the the smaller size of of of of the the the the the the the the the the infected infected infected red blood cell cell cell and and and a a a a a a a a a a a a a a a a a a a a coarser pigment pigment Note the the the the the the the the the the coarse coarse dark- brown pigment pigment pigment the the the the the the the the the the the parasite parasite lling the the the the the the the the the the the en en en en re re re re cell cell cell and and and the the the the the the the the the the the mbria on of of of the the the the the the the the the the the infected infected infected RBC RBC (I) RBC RBC showing a a a a a a a a a a a a a a a a a a P ovale microgametocyte Note the the the the the the the the di use pigment pigment inside the the the the the the the the parasite parasite and and the the the the the the the the ne ne Schu ner s s s s s s s dots of of the the the the the the the the infected infected cell cell 34