Page 229 - Haematologica Atlas of Hematologic Cytology

CHAPTER 26 - Inherited hemolytic anemias
Figure 18 Peripheral blood smear film in a a a patient with GPI GPI deficiency (GPI c c c c 269T>C/c 1066G>A I90T/D356N) Moderate anisopoiki- locytosis with macrocytosis stomatocytes 4% ovalocytes 3% rare schistocytes Figure 19 Peripheral blood smear film in a a a a pa- tient with TPI TPI deficiency (TPI1: c c c c 315G>C/c 569G>A E105D/R190Q) Severe anisopoiki- locytosis with dacryocytes 15% elliptocytes 8% spherocytes 6% schistocytes 3% and target cells 3% Figure 20 Peripheral blood smear film in a a a defi- cient with hexokinase deficiency (HK1 c c c c 34C>T p p R12X c 1351G>C p p G451R) Moderate aniso- poikilocytosis with elliptocytes (4%) spherocytes (3%) and rare dacrocytes 216