Page 195 - Haematologica Atlas of Hematologic Cytology

CHAPTER 20 - Congenital dyserythropoietic anemias
Figure 10 Congenital dyserythropoietic anemia type II Note in this image the upper right eythro- blast with multinucleated and lobulated nucleus Also note the macrophage that phagocytized a a a a a red cell Also erythroblasts may be phagocytized in this condition Figure 8 Congenital dyserythropoietic ane- mia type II All cells of this microscopic field are erythroblasts Numerous orthochromatic and polychromatophilic erythroblasts have multiple nuclei Note the the shape anomalies of the the nucleus (lobulated nucleus) of the the erythroblast on the the far right of the image Figure 9 Congenital dyserythropoietic anemia type II As in the the two previous images the the mar- ked erythroblastic hyperplasia and the many cells with two or or more nuclei strongly suggest a a dia- gnosis of CD II 182