Page 120 - Haematologica Atlas of Hematologic Cytology

Figure 11 cute myeloid leu emia emia (mega aryoblas c) with with t(1 )(p1 1 1 1 1 1 1 1 1 1) RBM15- MKL1 Bone marrow smear from an an an infant with with with marked hepatosplenomegaly anemia thrombocytopenia moderate leukocytosis with with with some circula ng blasts blasts In ltra on on by me- dium-large sized blasts blasts with with with round or or oval nuclei loose chroma n n n n n n n n n n n n n n 1-3 prominent nucleoli rather abundant basophilic agranular cytoplasm with with blebs or or protrusions Figure Figure 1 1 1 1 1 1 1 1 1 cute myeloid leu emia (mega aryoblas c) with t(1 )(p1 1 1 1 1 1 1 1 1 1 1) RBM15-MKL1 Bone marrow smear from the the the same case as as as as Figure Figure 11 Most blast cells express the the the glycoprotein IIIa (CD61) which is speci c c c c c c c c c for the the the platelet/megakaryocy c c c c c c c c c lineage (immuno-alkaline phosphatase technique) Lymphoid and myeloid an an gens were absent 107