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A. Al-Sharea et al.
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Figure 3. BPH/Apoe-/- mice have extramedullary hematopoiesis. Apoe-/- and BPH/ Apoe-/- mice were fed a WTD for 16 weeks after which flow cytometry was used to assess A) circulating monocytes(M)/neutrophils(N). B) Levels of BM HSPCs and C) proportion of HSPCs proliferating. D) Levels of BM GMPs and E) proportion of GMPs proliferating. F) Blood HSPC and MPC populations. G) Spleen HSPCs and GMPs were assessed along with H) proliferating HSPCs and GMPs. I) splenic monocyte(M)/neutrophil(N) populations. Data are presented as mean ± SEM where *P<0.05 and **P<0.01 (Student’s t-test). A-I) n= 5-11.
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haematologica | 2019; 104(3)
