Page 83 - 2020_08-Haematologica-web

Resolving mediators are altered in multiple sclerosis
Figure 1. Identification of lipid mediators. Lipid mediators were isolated from plasma of healthy subjects (n=15) and multiple sclerosis (MS) patients (n=38) and analyzed by liquid chromatography tandem mass spectrometry. Representative MRM illustration of arachidonic acid (AA)-derived prostaglandins, leukotrienes and lipoxins, docosahexaenoic acid (DHA)- derived resolvins and protectins, and eicosapentaenoic acid (EPA)-derived resolvins, and representative tandem mass spectrometry of AA-derived PGE2 and LXA4, DHA-derived RvD1, RvD5 and PD1.
haematologica | 2020; 105(8)
2059