Page 284 - Haematologica - Vol. 105 n. 6 - June 2020
P. 284
M. Salzmann et al.
F
GH
A
BC
D
E
Figure 3. Expression of iDTR does not change platelet function. (A) Representative histograms showing CD62P expression of CD41+ cells in diluted whole blood, stimulated with PAR4 agonist peptide (PAR4-AP), or convulxin (CVX), or treated with Tyrode’s HEPES buffer (TH). (B) Percentage CD62P+ and (C) activated GPIIb/IIIa+ of CD41+ events in diluted whole blood, stimulated with ADP, PAR4-AP or CVX (n=7-8). (D) Light transmission aggregometry of washed platelets stimulated with throm- bin or collagen I (n=3-5). (E) Representative histograms of CD41 expression of CD11b+, CD45+ events in blood, stimulated with PAR4-AP or CVX. (F) Percentage CD41+ of CD11b+, CD45+ events in whole blood, stimulated with ADP, PAR4-AP or CVX. (G) Sub classification into CD41+ side scatter medium monocytes and (H) side scatter high neutrophils (n=8).
1742
haematologica | 2020; 105(6)
