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Patterns of genetic alterations in B-NHL
Figure 1. Recurrently mutated genes in subtypes of B-cell non-Hodgkin lymphoma. An oncoplot shows significantly mutated genes, DNA copy number alterations (CNA) and translocations (Tx.) across our cohort of 685 B-cell non-Hodgkin lymphoma tumors. Mutation types and frequencies are summarized for each gene/CNA on the right, and the mutational burden for each case is shown at the top. DHL: double-hit lymphoma; THL: triple-hit lymphoma; HGBL-NOS: high-grade B-cell lym- phoma not otherwise specified; BL: Burkitt lymphoma; DLBCL: diffuse large B-cell lymphoma; FL: follicular lymphoma; MCL: mantle cell lymphoma.
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