Page 111 - 2022_03-Haematologica-web
P. 111
Dendritic cells in myelodysplastic syndromes
low-risk or high-risk myelodysplastic syn-
dromes. PLoS One. 2013;8(3):e57470.
60. Griffiths EA, Srivastava P, Matsuzaki J, et al. Clinical NY-ESO-1 Vaccination in com- bination with decitabine induces antigen- specific T-lymphocyte responses in patients with myelodysplastic syndrome.
Clin Cancer Res. 2018;24(5):1019-1029.
61. Srivastava P, Tzetzo SL, Gomez EC, et al. Inhibition of LSD1 in MDS progenitors restores differentiation of CD141Hi con- ventional dendritic cells. Leukemia.
2020;34(9):2460-2472.
62. See P, Dutertre CA, Chen J, et al. Mapping
the human DC lineage through the integra- tion of high-dimensional techniques.
Science. 2017;356(6342):eaag3009.
63. Maratheftis CI, Andreakos E, Moutsopoulos HM, Voulgarelis M. Toll- like receptor-4 is up-regulated in hematopoietic progenitor cells and con- tributes to increased apoptosis in myelodysplastic syndromes. Clin Cancer
Res. 2007;13(4):1154-1160.
64. Wei Y, Dimicoli S, Bueso-Ramos C, et al.
Toll-like receptor alterations in myelodys- plastic syndrome. Leukemia. 2013; 27(9):1832-1840.
65. Dimicoli S, Wei Y, Bueso-Ramos C, et al. Overexpression of the Toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic
syndromes. PLoS One. 2013;8(8):e71120. 66. Monlish DA, Bhatt ST, Schuettpelz LG. The role of Toll-like receptors in hematopoietic
malignancies. Front Immunol. 2016;7:390. 67. Velegraki M, Papakonstanti E, Mavroudi I, et al. Impaired clearance of apoptotic cells leads to HMGB1 release in the bone mar- row of patients with myelodysplastic syn- dromes and induces TLR4-mediated cytokine production. Haematologica.
2013;98(8):1206-1215.
68. Ignatz-Hoover JJ, Wang H, Moreton SA, et
al. The role of TLR8 signaling in acute myeloid leukemia differentiation. Leukemia. 2015;29(4):918-926.
haematologica | 2022; 107(3)
667