Page 198 - 2021_02-Haematologica-web

A. Sarkar et al.
6. Van Houten B, Woshner V, Santos JH. Role
of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair (Amst). 2006;5(2):145-152.
7. de Moura MB, dos Santos LS, Van Houten B. Mitochondrial dysfunction in neurodegen- erative diseases and cancer. Environ Mol Mutagen. 2010;51(5):391-405.
8. Diehn M, Cho RW, Lobo NA, et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature. 2009;458(7239):780-783.
9. Kroemer G, Pouyssegur J. Tumor cell metab- olism: cancer's Achilles' heel. Cancer Cell. 2008;13(6):472-482.
10. Liesa M, Palacin M, Zorzano A. Mitochondrial dynamics in mammalian health and disease. Physiol Rev. 2009;89(3): 799-845.
11. Westermann B. Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol. 2010;11(12):872-884.
12. Youle RJ, van der Bliek AM. Mitochondrial fission, fusion, and stress. Science. 2012;337(6098):1062-1065.
13. Narendra DP, Jin SM, Tanaka A, et al. PINK1 is selectively stabilized on impaired mito- chondria to activate Parkin. PLoS Biol. 2010;8(1):e1000298.
14. Youle RJ, Narendra DP. Mechanisms of mitophagy. Nat Rev Mol Cell Biol. 2011;12 (1):9-14.
15. Pickrell AM, Youle RJ. The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease. Neuron. 2015;85(2): 257-273.
16. Ditch S, Paull TT. The ATM protein kinase and cellular redox signaling: beyond the DNA damage response. Trends Biochem Sci. 2012;37(1):15-22.
17. Lavin MF, Shiloh Y. Ataxia-telangiectasia: a multifaceted genetic disorder associated with defective signal transduction. Curr Opin Immunol. 1996;8(4):459-464.
18. Udayakumar D, Horikoshi N, Mishra L, et al. Detecting ATM-dependent chromatin modification in DNA damage response. Methods Mol Biol. 2015;1288:317-336.
19. Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nature Rev Cancer. 2003;3(3):155-168.
20. You Z, Shi LZ, Zhu Q, et al. CtIP links DNA double-strand break sensing to resection. Mol Cell. 2009;36(6):954-969.
21. Barlow C, Ribaut-Barassin C, Zwingman TA, et al. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proc Natl Acad Sci U S A. 2000;97(2):871-876.
22. Lim DS, Kirsch DG, Canman CE, et al. ATM binds to beta-adaptin in cytoplasmic vesi- cles. Proc Natl Acad Sci U S A. 1998;95(17): 10146-10151.
23. Valentin-Vega YA, Maclean KH, Tait-Mulder J, et al. Mitochondrial dysfunction in ataxia- telangiectasia. Blood. 2012;119(6):1490- 1500.
24. Eaton JS, Lin ZP, Sartorelli AC, et al. Ataxia- telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis. J Clin Invest. 2007;117(9): 2723-2734.
25. Ambrose M, Goldstine JV, Gatti RA. Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells. Hum Mol Genet. 2007;16(18):2154-2164. Schaffner C, Idler I, Stilgenbauer S, et al. Mantle cell lymphoma is characterized by inactivation of the ATM gene. Proc Natl Acad Sci U S A. 2000;97(6):2773-2778.
links the inner and outer mitochondrial
membranes. Cell. 2000;101(4):401-412.
37. Lazarou M, Sliter DA, Kane LA, et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature.
2015;524(7565):309-314.
38. Bakkenist CJ, Kastan MB. DNA damage
activates ATM through intermolecular autophosphorylation and dimer dissocia- tion. Nature. 2003;421(6922):499-506.
39. Lee JH, Paull TT. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene. 2007;26 (56):7741-7748.
40. Hang L, Thundyil J, Lim KL. Mitochondrial dysfunction and Parkinson disease: a Parkin- AMPK alliance in neuroprotection. Ann N Y Acad Sci. 2015;1350: 37-47.
41. Kazlauskaite A, Muqit MM. PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease. FEBS J. 2015;282(2):215- 223.
42. Gong Y, Zack TI, Morris LG, et al. Pan-can- cer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat Genet. 2014;46(6):588-594.
43.Bea S, Valdes-Mas R, Navarro A, et al. Landscape of somatic mutations and clonal evolution in mantle cell lymphoma. Proc Natl Acad Sci U S A. 2013 ;110(45):18250- 18255.
44. Campo E, Rule S. Mantle cell lymphoma: evolving management strategies. Blood. 2015;125(1):48-55.
45.Narendra D, Tanaka A, Suen DF, et al. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol. 2008;183(5):795-803. Riley BE, Lougheed JC, Callaway K, et al. Structure and function of Parkin E3 ubiqui- tin ligase reveals aspects of RING and HECT ligases. Nat Commun. 2013;4:1982-1997.
47.Wauer T, Komander D. Structure of the human Parkin ligase domain in an autoin- hibited state. EMBO J. 2013;32(15):2099- 2112.
48. Trempe JF, Sauve V, Grenier K, et al. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science. 2013;340(6139):1451-1455.
49. Qi Y, Qiu Q, Gu X, et al. ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Sci Rep. 2016;6:24700.
50. Kang HT, Park JT, Choi K, et al. Chemical screening identifies ATM as a target for alle- viating senescence. Nat Chem Biol. 2017;13(6):616-623.
26.
27.
Fang NY, Greiner TC, Weisenburger DD, et al. Oligonucleotide microarrays demon- strate the highest frequency of ATM muta- tions in the mantle cell subtype of lym- phoma. Proc Natl Acad Sci U S A. 2003;100(9):5372-5377.
28. Venegas V, Halberg MC. Measurement of mitochondrial DNA copy number. Methods Mol Biol. 2012;837:327-335.
29. Amin HM, McDonnell TJ, Medeiros LJ, et al. Characterization of 4 mantle cell lym- phoma cell lines. Arch Pathol Lab Med. 2003;127(4):424-431.
30.Vorechovsky I, Luo L, Dyer MJ, et al. Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T- cell leukaemia. Nat Genet. 1997;17(1):96-99.
31. Salaverria I, Perez-Galan P, Colomer D, et al. Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives. Haematologica. 2006;91(1):11- 16.
32. Pawlyk AC, Giasson BI, Sampathu DM, et al. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J Biol Chem. 2003;278(48):48120-48128.
33. Chaugule VK, Burchell L, Barber KR, et al. Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J. 2011;30 (14):2853-2867.
34. Yamano K, Youle RJ. PINK1 is degraded through the N-end rule pathway. Autophagy. 2013;9(11):1758-1769.
35.Schwanhausser B, Busse D, Li N, et al. Global quantification of mammalian gene expression control. Nature. 2011;473(7347): 337-342.
36. Donzeau M, Kaldi K, Adam A, et al. Tim23
46.
512
haematologica | 2021; 106(2)