Page 264 - Haematologica Atlas of Hematologic Cytology

Figure 4 Bone marrow marrow The main feature of of bone marrow marrow is the abundance of of mega- karyocytes karyocytes although in a
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few cases the number of megakaryocytes is normal or or even reduced due to to autoan bodies that a
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ect megakaryopoiesis (Top center) A very large cytoplasm fragment of a
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mature megakaryocyte that has probably been destroyed du- ring smear prepara on (Center) An immature megakaryocyte is is undergoing mitosis Figure 5 one marrow in vans vans syndrome syndrome Evans syndrome syndrome is de ned by the concur- rent or sequen al occurrence of immune immune thrombocytopenia
and autoimmune hemoly c c c c c anemia anemia In this pa ent ent thrombocytopenia
and and hemoly c c c c anemia anemia were concurrent and and the gure shows a
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large mature megkaryocyte and erythroid hyperplasia with many normal erythroblasts at at di erent stages of matura on 251