Page 209 - Haematologica Atlas of Hematologic Cytology

CHAPTER 24 - Anemia of chronic in ammation
Figure 1 nemia nemia of chronic inflammation Bone marrow smear from a a a a a a a a a a a a a patient with with Hodgkin lymphoma mild anemia and red cell cell indices within reference ranges Marrow is normocellular with with no no no evidence of of tumor infiltration A high myeloid-to-erythroid ratio ratio and and a a a a a a a a a a a slight increase in in in in eosinophils can be observed but morphology of of the erythroid and and granulocytic precursors is unremarkable Figure Figure nemia of of of chronic in in in in amma on on on on Bone marrow smear from the the same case as as as in in in in in in Figure Figure 1 showing accumula ons of of of of small sidero c c c c c c c c c c granules in in in in in in the the the cytoplasm cytoplasm of of of of two macrophages (le ) ) Perls reac on on on on reveals abundant stainable iron in in in in in in the the cytoplasm cytoplasm of of of a a a a a a a a a a a a a a a a a a a a a a macrophage macrophage (right) It should be noted that trephine biopsy sec ons are less reliable than the the aspirate for the the assessment of storage iron which is removed by decalci ca ca on on on 196