Page 160 - Haematologica-5

N. Gagelmann et al.
Table 1. Patients’, disease and transplantation characteristics. Patients without EMD
Patients with EMD EM group
139 (3.7)
57 (41.0)
82 (59.0)
59.0 31.8 to 72.8
29 (30.5) 29 (30.5) 37 (38.9) 44
85 (65.9) 44 (34.1) 10
81 (62.8) 48 (37.2) 10
16 (11.7) 109 (79.6) 12 (8.8) 2
39 (28.3) 3 (2.2) 96 (69.6) 1
72 (73.5) 22 (22.4) 4 (4.1) 41
73 (55.7) 58 (44.3) 8
115 (82.7) 24 (17.3)
25 (18.0) 62 (44.6) 52 (37.4)
6.1 3.9 to 11.9
15
124
Characteristic
N. of patients (%)
Sex, n. (%)
Female
Male
Age at diagnosis in years
Median
Range
ISS, n. (%)
I
II
III Unknown
Renal function, n. (%) A
B
Unknown
Karnofsky score, n. (%)
Good Poor Unknown
Status at ASCT, n. (%) CR
PR
< PR Unknown
Type of myeloma, n. (%)
Light chain only Non-secretory Heavy and light chain Unknown
Ig-type, n. (%) G
A
D/E/M Unknown
Light chain type, n. (%)
Kappa Lambda Unknown
Years of ASCT, n. (%) 0
1
< 2009 2009-11 > 2011
Time to 1st ASCT in months Median
Range
Type of ASCT, n.
Tandem
Single
MM group
3062 (81.8)
1279 (41.8)
1783 (58.2)
59.8 27.4 to 77.7
781 (36.9) 759 (35.8) 578 (27.3) 944
2188 (82.7) 458 (17.3) 416
1877 (67.3) 914 (32.7) 271
580 (19.1) 2262 (74.7) 187 (6.2) 33
672 (22.1) 74 (2.4) 2292 (75.4) 24
1648 (70.8) 634 (27.2) 45 (1.9) 735
1853 (63.7) 1054 (36.3) 155
3062 (100)
518 (16.9) 1400 (45.7) 1144 (37.4)
6.2 1.1 to 11.9
249
2813
PS group
543 (14.5)
240 (44.2)
303 (55.8)
59.8 26.8 to 76.8
158 (38.6) 148 (36.2) 103 (25.2) 134
410 (83.2) 83 (16.8) 50
344 (67.7) 164 (32.3) 35
115 (21.5) 389 (72.6) 32 (6.0) 7
122 (22.5) 29 (5.4) 389 (72.0) 3
282 (72.1) 101 (25.8) 8 (2.0) 152
327 (65.1) 175 (34.9) 41
524 (96.5) 19 (3.5)
82 (15.1) 204 (37.6) 257 (47.3)
6.2 2.1 to 11.9
89
454
Total P 3744
1576 (42.1) 0.55
2168 (57.9)
0.59
968 (36.9)
936 (35.7) 0.11 781 (27.4)
1122
2683 (82.1) 585 (17.9) 476
<0.001
2302 (67.2)
1126 (32.8) 0.55
316
711 (19.2)
2760 (74.6) 0.10
231 (6.2) 42
833 (22.4)
106 (2.9) 0.002
2777 (74.7)
28
2002 (71.1)
757 (26.9) 0.51
57 (2.0) 928
2253 (63.6) 0.13 1287 (36.4)
≥ 2
Years of ASCT, n. (%)
204
3062 (81.8) 639 (17.1) 43 (1.1)
<0.001
625 (16.7) 0.001 1666 (44.5)
1453 (38.8)
0.81
353
3391
892
EMD: extramedullary disease; MM: patients without extramedullary disease; PS: paraskeletal involvement; EM: extramedullary organ involvement; N.: number; ISS: International Staging System; ASCT: autologous stem cell transplantation; CR: complete remission; PR: partial remission.
haematologica | 2018; 103(5)