Page 245 - Haematologica - Vol. 105 n. 6 - June 2020
P. 245

 The FVIII binding site on VWF
   factor binding in Weibel-Palade bodies in endothelial cells. PLoS One. 2011;6 (8):e24163.
29. Purvis AR, Gross J, Dang LT, et al. Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi. Proc Natl Acad Sci U S A. 2007;104(40):15647-15652.
30. Dong X, Leksa NC, Chhabra ES, et al. The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis. Blood. 2019;133(14):1523-1533.
31. Dimitrov JD, Christophe OD, Kang J, et al. Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.
Biochemistry. 2012;51(20):4108-4116.
32. Owen WG, Wagner RH. Antihemophilic factor: separation of an active fragment fol- lowing dissociation by salts or detergents. Thromb Diath Haemorrh. 1972;27(3):502-
515.
33. Marcsisin SR, Engen JR. Hydrogen
exchange mass spectrometry: what is it and what can it tell us? Anal Bioanal Chem. 2010;397(3):967-972.
34. Morgan CR, Engen JR. Investigating solu- tion-phase protein structure and dynamics by hydrogen exchange mass spectrometry. Curr Protoc Protein Sci. 2009;Chapter 17:Unit 17.6.1-17.
35. Schneppenheim R, Budde U, Drewke E, et al. Results of a screening for von Willebrand disease type 2N in patients with suspected haemophilia A or von Willebrand disease type 1. Thromb Haemost. 1996;76(4):598-602.
36. Dagil L, Troelsen KS, Bolt G, et al. Interaction Between the a3 Region of Factor VIII and the TIL’E’ Domains of the von Willebrand Factor. Biophys. J. 2019;117(3):479-489.
37. de Jong A, Eikenboom J. Von Willebrand disease mutation spectrum and associated mutation mechanisms. Thromb Res. 2017;159:65-75.
haematologica | 2020; 105(6)
  1703
  


















































































   243   244   245   246   247