Page 98 - 2019_10 resto del Mondo_web
P. 98

F. Yang et al.
for biological and clinical consideration. J
Exp Med. 2013;210(2):205-208.
11. Livnah O, Stura EA, Middleton SA,
Johnson DL, Jolliffe LK, Wilson IA. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science. 1999;283 (5404): 987-990.
12. Witthuhn BA, Quelle FW, Silvennoinen O, et al. JAK2 associates with the erythropoi- etin receptor and is tyrosine phosphorylat- ed and activated following stimulation with erythropoietin. Cell. 1993;74(2):227- 236.
13. Socolovsky M, Fallon AE, Wang S, Brugnara C, Lodish HF. Fetal anemia and apoptosis of red cell progenitors in Stat5a-/- 5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell. 1999;98(2):181-191.
14. Clem RJ, Cheng EH, Karp CL, et al. Modulation of cell death by Bcl-XL through caspase interaction. Proc Natl Acad Sci U S A. 1998;95(2):554-559.
15. Vardaki I, Sanchez C, Fonseca P, et al. Caspase-3-dependent cleavage of Bcl-xL in the stroma exosomes is required for their uptake by hematological malignant cells. Blood. 2016;128(23):2655-2665.
16. Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental check- point in definitive hematopoiesis. Cell. 1998;93(3):397-409.
17. Raghupathy R, Anilkumar AA, Polley A, et al. Transbilayer lipid interactions mediate nanoclustering of lipid-anchored proteins. Cell. 2015;161(3):581-594.
18. Devaux PF. Static and dynamic lipid asym- metry in cell membranes. Biochemistry. 1991;30(5):1163-1173.
19. Sprong H, van der Sluijs P, van Meer G. How proteins move lipids and lipids move proteins. Nat Rew Mol Cell Biol. 2001;2(7):504-513.
20. Leventis PA, Grinstein S. The distribution and function of phosphatidylserine in cellu- lar membranes. Annu Rev Biophys. 2010;39:407-427.
21. Daleke DL, Lyles JV. Identification and purification of aminophospholipid flippas- es. Biochim Biophys Acta. 2000;1486(1): 108-127.
22. Segawa K, Kurata S, Yanagihashi Y, Brummelkamp TR, Matsuda F, Nagata S. Caspase-mediated cleavage of phospho- lipid flippase for apoptotic phos- phatidylserine exposure. Science. 2014;344 (6188):1164-1168.
23. Zwaal RF, Comfurius P, Bevers EM. Surface exposure of phosphatidylserine in patho- logical cells. Cell Mol Life Sci. 2005;62(9): 971-988.
24. Kosan C, Saba I, Godmann M, et al. Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differen- tiation. Immunity. 2010;33(6):917-928.
25. Wang H, Diao D, Shi Z, et al. SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling. Cell Stem Cell. 2016;18(4):495-507.
26. Pietkiewicz S, Schmidt JH, Lavrik IN. Quantification of apoptosis and necropto- sis at the single cell level by a combination of Imaging Flow Cytometry with classical Annexin V/propidium iodide staining. J Immunol Methods. 2015;423:99-103.
27. Gaudreau MC, Grapton D, Helness A, et al. Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells. Sci Rep. 2016;6:27379.
28. Menon MP, Fang J, Wojchowski DM. Core erythropoietin receptor signals for late ery- throblast development. Blood. 2006;107(7): 2662-2672.
29. Zhang J, Socolovsky M, Gross AW, Lodish
HF. Role of Ras signaling in erythroid differ- entiation of mouse fetal liver cells: func- tional analysis by a flow cytometry-based novel culture system. Blood. 2003;102 (12):3938-3946.
30. Qu X, Zhang S, Wang S, et al. TET2 defi- ciency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors. Blood. 2018;132(22):2406- 2417.
31. Yan H, Wang Y, Qu X, et al. Distinct roles for TET family proteins in regulating human erythropoiesis. Blood. 2017;129 (14):2002-2012.
32. Huang Y, Hale J, Wang Y, et al. SF3B1 defi- ciency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS. J Hematol Oncol. 2018;11(1):19.
33. Paulusma CC, Folmer DE, Ho-Mok KS, et al. ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity. Hepatology. 2008;47(1):268-278.
34. Paulusma CC, Oude Elferink RP. The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease. Biochim Biophys Acta. 2005;1741(1-2):11-24.
35. Siggs OM, Arnold CN, Huber C, et al. The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nat Immunol. 2011;12(5):434-440.
36. Wu H, Liu X, Jaenisch R, Lodish HF. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin recep- tor. Cell. 1995;83(1):59-67.
37. Metcalf D. Hematopoietic cytokines. Blood. 2008;111(2):485-491.
38. Li N, Yang Y, Liang C, et al. Tmem30a Plays Critical Roles in Ensuring the Survival of Hematopoietic Cells and Leukemia Cells in Mice. Am J Pathol. 2018;188(6):1457-1468.
1994
haematologica | 2019; 104(10)


































































































   96   97   98   99   100