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Burkitt-like lymphoma with 11q aberration
A1 B1
A2 A3 B2
C1 D1
B3
C2 D2
Figure 1. Morphological features of cases of Burkitt-like lymphoma with 11q aberration. (A1-A3) Case #2 shows the typical morphology of diffuse large B-cell lym- phomas with large and irregular cells resembling centroblasts. This case was positive for (A2) LMO2 and negative for (A3) MYC. (B1-B3) Case #4 corresponds to a tumor with high-grade B-cell lymphoma (HGBCL) morphology. It is composed mostly of medium-sized cells with mild heterogeneity. Note the “starry sky” pattern. This case was positive for (B2) MYC and (B3) LMO2 expression. (C1-C2; case #7) Lymph node with nodular architecture and a “starry sky” pattern with large follicles and a disrupted follicular cell meshwork highlighted with (C2) CD21. (D1-D2; case #5) This is a case with HGBCL features with expression of (D2) BCL2 in the neoplastic cells.
haematologica | 2019; 104(9)
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