Page 57 - Haematologica July

Mouse model of sickle cell disease
care utilization for adult sickle cell patients: The PiSCES Project. J Womens Health (Larchmt). 2006;15(2):146-154.
39. Ryan TM, Ciavatta DJ, Townes TM. Knockout-transgenic mouse model of sick- le cell disease. Science. 1997;278(5339):873- 876.
40. Nevitt SJ, Jones AP, Howard J. Hydroxyurea (hydroxycarbamide) for sick- le cell disease. Cochrane Database Syst Rev. 2017;4:CD002202.
41. Ehrenreich H, Andereson RW, Fox CH, et al. Endothelins, peptides with potent vasoactive properties, are produced by human macrophages. J Exp Med. 1990; 172(6):1741-1748.
42. Bremnes T, Paasche JD, Mehlum A, Sandberg C, Bremnes B, Attramadal H. Regulation and intracellular trafficking pathways of the endothelin receptors. J Biol Chem. 2000;275(23):17596-17604.
43. Hansen-Schwartz J, Svensson CL, Xu CB,
Edvinsson L. Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery. Br J Pharmacol. 2002;137(1):118-126.
44. Gold M, Levine J, Correa A. Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat senso- ry neurons in vitro. J Neurosci. 1998;18(24):10345-10355.
45. England S, Bevan S, Docherty RJ. PGE2 modulates the tetrodotoxin-resistant sodi- um current in neonatal rat dorsal root gan- glion neurones via the cyclic AMP-protein kinase A cascade. J Physiol. 1996;495(Pt 2):429-440.
46. Feng B, Strichartz G. Endothelin-1 raises excitability and reduces potassium currents in sensory neurons. Brain Res Bull. 2009; 79(6):345-350.
47. Berti-Mattera LN, Larkin B, Hourmouzis Z, Kern TS, Siegel RE. NF-κB subunits are dif-
ferentially distributed in cells of lumbar dorsal root ganglia in naive and diabetic rats. Neurosci Lett. 2011;490(1):41-45.
48. Cang CL, Zhang H, Zhang YQ, Zhao ZQ. PKCepsilon-dependent potentiation of TTX-resistant Nav1.8 current by neu- rokinin-1 receptor activation in rat dorsal root ganglion neurons. Mol Pain. 2009;5:33.
49. Satoh A, Gukovskaya AS, Nieto JM, et al. PKC-d and -ε regulate NF-κB activation induced by cholecystokinin and TNF-alpha in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2004; 287(3):G582-591.
50. Clerk A, Bogoyevitch MA, Anderson MB, Sugden PH. Differential activation of pro- tein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem. 1994; 269(52):32848-32857.
haematologica | 2018; 103(7)
1135