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αβTCR signaling acts as a tumor suppressor
Funding
This work was supported by grants from LYSARC-Institut CARNOT CALYM-ANR (#R14-2014, #R20-2015, #R29- 2016, #R31-2017), CNRS and INSERM. TC was supported by grants from Canceropôle PACA and la Fondation pour la Recherche Médicale (ING20121226364). ML was a recipient of a fellowship from INCa (#ASC12035ASA). SOM is supported by a fellowship from Aix-Marseille Université. JAN is supported by a grant from Fondation pour la Recherche Médicale (Equipe FRM DEQ20140329534).
Acknowledgments
The authors thank the European Mouse Mutant Archives (EMMA) for providing Ptenflox/flox mice, Charles Pignon and Maeva Patry for mice genotyping, Virginie Fouilloux (Cardiac Surgery Department, APHM, Marseille, France) for providing human thymus, Marie Malissen for providing CD4-Cre and HY mice, the CRCM cytometry platform for phosphoflow FACS analysis and Philippe Naquet for the critical reading of the man- uscript.
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