Page 77 - Haematologica May 2022
P. 77

 Defective eNOS and angiogenesis in GATA2 R398W
   enhancing endothelial nitric oxide syntase (eNOS) expression and preventing eNOS uncoupling. Br J Pharmacol. 2011;164(2): 213-223.
45. Marsden PA, Heng HH, Scherer SW, et al. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem. 1993;268(23):17478-17488.
46. Robinson LJ, Weremowicz S, Morton CC, Michel T. Isolation and chromosomal local- ization of the human endothelial nitric oxide synthase (NOS3) gene. Genomics. 1994;19(2):350-357.
47. Garcia V, Sessa WC. Endothelial NOS: per- spective and recent developments. Br J Pharmacol. 2019;176(2):189-196.
48. Zemankova L, Varejckova M, Dolezalova E, et al. Atorvastatin-induced endothelial nitric oxide synthase expression in
endothelial cells is mediated by endoglin. J
Physiol Pharmacol. 2015;66(3):403-413. 49.Laufs U, La Fata V, Plutzky J, Liao JK. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation. 1998;97(12):1129-
1135.
50.Momi S, Monopoli A, Alberti PF, et al.
Nitric oxide enhances the anti-inflammato- ry and anti-atherogenic activity of atorvas- tatin in a mouse model of accelerated ath- erosclerosis. Cardiovasc Res. 2012;94(3): 428-438.
51. Kaur S, Rawal P, Siddiqui H, et al. Increased expression of RUNX1 in liver correlates with NASH activity score in patients with non-alcoholic steatohepatitis (NASH). Cells. 2019;8(10):1277.
52.Wilson NK, Foster SD, Wang X, et al. Combinatorial transcriptional control in
53.
blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regula- tors. Cell Stem Cell. 2010;7(4):532-544. Bresciani E, Carrington B, Kwon Kim EM, et al. GATA2 is required for the runx1-inde- pendent hematopoiesis in Zebrafish. Blood 2019; 134 (Suppl 1):2463
54.Blum A, Shamburek R. The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodula- tion and thrombogenesis. Atherosclerosis. 2009;203(2);325-330.
55.Oesterle A, Laufs U, Liao JK. Pleiotropic effects of statins on the cardiovascular sys- tem. Circ Res. 2017;120(1):229-243.
56.Paciullo F, Momi S, Gresele P. PCSK9 in haemostasis and thrombosis: possible pleiotropic effects of PCSK9 inhibitors in cardiovascular prevention. Thromb Haemost. 2019;119(3):359-367.
haematologica | 2022; 107(5)
  1085
  














































































   75   76   77   78   79