Page 169 - Haematologica May 2022

RCT of geriatric consultation in blood cancers
for all patients could have contributed to a more effective geriatrics-led intervention.
Reducing mortality is not necessary to justify the integra- tion of geriatrics into the care of patients with blood can- cers. Emerging evidence from other trials of predominantly patients with solid tumors suggests that GA-driven inter- ventions improve meaningful outcomes other than survival
A
in older patients with cancer, including decreased treatment toxicity and improvements across multiple domains of quality of life.16,17,27,28,36,37 Various models of GA-driven inter- ventions were studied in these trials, ranging from a GA summary with recommended interventions carried out by the treating hematologic oncologist, to an embedded co- management model led by a geriatrician (as described
B
Figure 2. One-year overall survival by standard oncologic care (control) versus geriatric consultation + standard care. (A) Intent-to-treat analysis. (B) Per-protocol analysis.
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