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R.J. Lin et al.
cohorts.7-9 It should also be noted that based on the CARG risk score, our cohort was much frailer than the original CARG patient populations with more than half in the high-risk group.13,14 Moreover, we found that a senes- cence-associated, proinflammatory CK milieu, which was
AB
readily reversed by prephase treatment, was significantly associated with GA-defined, prognostically important geriatric impairments in function, mobility, and chemotherapy toxicity risk. While our sample size and event rate are too small to definitively associate GA meas-
CD
Figure 2. Survival out- comes. (A) Kaplan-Meier survival estimate of pro- gression-free survival (PFS) (red-line with shad- ed area denoted 95% con- fidence interval). Life table is listed below. (B) Kaplan- Meier survival estimate of overall survival (OS)(red- line with shaded area denoted 95% confidence interval). Life table is listed below. (C) Kaplan-Meier survival estimate of PFS by AA-IPI (red-line denoted low/low-intermediate and blue-line denoted high- intermediate/high cate- gories). Life table is listed below. (D) Kaplan-Meier survival estimate of OS by AA-IPI (red-line denoted low/low-intermediate and blue-line denoted high- intermediate/high cate- gories). Life table is listed below.
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