Page 119 - 2022_01-Haematologica-web
P. 119
RNA-sequencing of fusion genes in AML
cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia. Leuk Lymphoma. 2018;59(3):725-732.
25. Hollink IHIM, van den Heuvel-Eibrink MM, Arentsen-Peters STCJM, et al. NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern. Blood. 2011;118(13):3645-3656.
26. Bisio V, Zampini M, Tregnago C, et al. NUP98-fusion transcripts characterize dif- ferent biological entities within acute myeloid leukemia: a report from the AIEOP- AML group. Leukemia. 2017;31(4):974-977.
27. Kearney L. t(5;11)(q35;p15.5) NUP98/NSD1. Atlas Genet Cytogenet Oncol Haematol. 2002;6(3):209-211. http://atlasgeneticsoncol- ogy.org/Anomalies/t0511q35p15ID1209.ht ml (2002, accessed April 28, 2020).
28. Heyer EE, Deveson IW, Wooi D, et al. Diagnosis of fusion genes using targeted RNA sequencing. Nat Commun. 2020;11(1): 1810.
29. Conesa A, Madrigal P, Tarazona S, et al. A survey of best practices for RNA-seq data
analysis. Genome Biol. 2016;17(1):13.
30. Gröschel S, Sanders MA, Hoogenboezem R, et al. A single oncogenic enhancer rearrange- ment causes concomitant EVI1 and GATA2 deregulation in Leukemia. Cell. 2014;157(2):
369-381.
31. Yamazaki H, Suzuki M, Otsuki A, et al. A
remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. Cancer Cell. 2014;25(4):415-427.
32.Castet A, Boulahtouf A, Versini G, et al. Multiple domains of the Receptor- Interacting Protein 140 contribute to tran- scription inhibition. Nucleic Acids Res. 2004;32(6):1957-1966.
33. Lapierre M, Castet-Nicolas A, Gitenay D, et al. Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia. J Hematol Oncol. 2015;8:20.
34. Herold T, Jurinovic V, Metzeler KH, et al. An eight-gene expression signature for the pre- diction of survival and time to treatment in chronic lymphocytic leukemia. Leukemia. 2011;25(10):1639-1645.
35. ZhangR,KimYM,YangX,LiY,LiS,LeeJY. A possible 5’-NRIP1/UHRF1-3’ fusion gene detected by array CGH analysis in a Ph+ ALL patient. Cancer Genet. 2011;204(12): 687-691.
36. Emmrich S, Streltsov A, Schmidt F, Thangapandi VR, Reinhardt D, Klusmann JH. LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia. Mol Cancer. 2014;13(1):171.
37.Emmrich S, Rasche M, Schöning J, et al. miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFb and Wnt signaling. Genes Dev. 2014;28(8):858-874.
38. Stengel A, Shahswar R, Haferlach T, et al. Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS. Blood Adv. 2020;4(21):5393-5401.
39. Haferlach C, Walter W, Meggendorfer M, et al. The diverse landscape of fusion tran- scripts in 25 different hematological entities. Blood. 2020;136(Suppl 1):16-17.
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