Page 186 - 2021_06-Haematologica-web
P. 186

S. Warsi et al.
17. Zhang J, Niu C, Ye L, et al. Identification of
the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425(6960):836-841.
18. Goldman DC, Bailey AS, Pfaffle DL, Al Masri A, Christian JL, Fleming WH. BMP4 regulates the hematopoietic stem cell niche. Blood. 2009;114(20):4393-4401.
19. Bhatia M, Bonnet D, Wu D, et al. Bone morphogenetic proteins regulate the devel- opmental program of human hematopoiet- ic stem cells. J Exp Med. 1999;189(7):1139- 1148.
20. Khurana S, Buckley S, Schouteden S, et al. A novel role of BMP4 in adult hematopoi- etic stem and progenitor cell homing via Smad independent regulation of integrin- alpha4 expression. Blood. 2013;121(5):781- 790.
21. Singbrant S, Karlsson G, Ehinger M, et al. Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture. Blood. 2010;115(23):4689-4698.
22.Singbrant S, Moody JL, Blank U, et al. Smad5 is dispensable for adult murine hematopoiesis. Blood. 2006;108(12):3707- 3712.
23. Utsugisawa T, Moody JL, Aspling M, Nilsson E, Carlsson L, Karlsson S. A road map toward defining the role of Smad sig- naling in hematopoietic stem cells. Stem Cells. 2006;24(4):1128-1136.
24. Blank U, Brown A, Adams DC, Karolak MJ, Oxburgh L. BMP7 promotes proliferation
of nephron progenitor cells via a JNK- dependent mechanism. Development. 2009;136(21):3557-3566.
25. Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF- beta family signalling. Nature. 2003;425(6958):577-584.
26. Monteiro RM, de Sousa Lopes SM, Bialecka M, de Boer S, Zwijsen A, Mummery CL. Real time monitoring of BMP Smads transcriptional activity during mouse development. Genesis. 2008;46(7): 335-346.
27. Beppu H, Lei H, Bloch KD, Li E. Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis. 2005;41(3):133-137.
28. Stadtfeld M, Graf T. Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing. Development. 2005;132(1): 203-213.
29. Pronk CJ, Rossi DJ, Mansson R, et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloery- throid progenitor cell hierarchy. Cell Stem Cell. 2007;1(4):428-442.
30. Chen MJ, Yokomizo T, Zeigler BM, Dzierzak E, Speck NA. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature. 2009;457(7231):887-891.
31. Gekas C, Graf T. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood. 2013;121(22):4463-4472.
32. Blank U, Seto ML, Adams DC,
33.
34.
Wojchowski DM, Karolak MJ, Oxburgh L. An in vivo reporter of BMP signaling in organogenesis reveals targets in the devel- oping kidney. BMC Dev Biol. 2008;8:86. Crisan M, Kartalaei PS, Vink CS, et al. BMP signalling differentially regulates distinct haematopoietic stem cell types. Nat Commun. 2015;6:8040.
Crisan M, Solaimani Kartalaei P, Neagu A, et al. BMP and hedgehog regulate distinct AGM hematopoietic stem cells ex vivo. Stem Cell Reports. 2016;6(3):383-395.
35.Karlsson G, Rorby E, Pina C, et al. The tetraspanin CD9 affords high-purity cap- ture of all murine hematopoietic stem cells. Cell Rep. 2013;4(4):642-648.
36. Jeanpierre S, Nicolini FE, Kaniewski B, et al. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoi- etin signaling. Blood. 2008;112(8):3154- 3163.
37. Xu J, Lim SB, Ng MY, et al. ZO-1 regulates Erk, Smad1/5/8, Smad2, and RhoA activi- ties to modulate self-renewal and differen- tiation of mouse embryonic stem cells. Stem Cells. 2012;30(9):1885-1900.
38. Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science. 2002;298(5593): 597-600.
39.
Bruno L, Hoffmann R, McBlane F, et al. Molecular signatures of self-renewal, differ- entiation, and lineage choice in multipoten- tial hemopoietic progenitor cells in vitro. Mol Cell Biol. 2004;24(2):741-756.
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