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J.A. Sparano et al.
cycles of therapy. The characteristics of the entire study population, and patients who received four or fewer versus five or six cycles are shown in Table 1. The characteristics of the two groups were generally comparable to each other, and to those of the entire study population, with respect to gender, median age, baseline CD4 count, con- current antiretroviral therapy, histology, and bone marrow involvement at baseline.
Information regarding histological subtype (germinal
center B-cell [GCB] subtype vs. non-GCB subtype) was available for only 21 of the 64 patients who had a com- plete response, with no significant difference in number with non-GCB subtype for those who received four or fewer cycles compared with those who received five or six cycles (3/8 vs. 5/13 patients, P=1.000 Fisher exact test).
Treatment administered
A total of 322 cycles of EPOCH therapy were given to
Figure 1. Consort diagram.
732
haematologica | 2021; 106(3)