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ASCT for progressive SSc
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Figure 1. Kaplan-Meier curves of outcomes of patients undergoing autologous hematopoietic stem cell transplantation for severe systemic sclero- sis. Overall survival (OS), progression-free survival (PFS), progression and non-relapse (treatment)- related mortality (NRM) over time.
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Figure 2. Boxplots of the four most important efficacy parameters in the 24 months following autologous hematopoietic stem cell transplantation for severe sys- temic sclerosis. (A) Improvement of the modified Rodnan skin score (mRSS) (n=55; P<0.001). (B) Improvement of forced vital capacity (FVC) (n=37; P=0.001. (C) Stabilization of diffusion capacity of carbon monoxide (DLCO) (n=35; P=0.01). (D) Improvement of Scleroderma Health Assessment Questionnaire (sHAQ) score (n=15, P=0.001).
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