Page 38 - Haematologica Atlas of Hematologic Cytology

The hematologic changes observed in in in human immunodeficiency virus (HIV) infection are reported in in in Table 1 While in in in the the early stages of infection the the bone marrow aspirate shows normal cellularity with possible infiltration by lymphocytes and plasma cells in the the advanced stages of the the disease bone marrow is is generally hypocellular this feature in in association with the appearance of reticulin fibrosis makes bone marrow aspiration difficult Therefore a trephine biopsy should be performed in in in order to identify possible opportunistic infections
often mycobacterial parasitic or or fungal or or a a a a a a a lymphomatous involvement References
Palmer L L Briggs C C McFadden S S et al al al al ICSH recommenda ons
for the standardiza on on of of nomenclature and and grading of of peripheral blood cell morphological features Int J Lab Hematol 2015 37(3):287-303 ini G Bain B B B Be elheim P et et al al A European European consensus report on on on on on blood cell iden ca ca on: terminology u u u u u u lized and morphological diagnosis concordance among 28 experts from 17 countries within the the European European LeukemiaNet
network WP10 on on on behalf of the the ELN Morphology Faculty Br J Haematol 2010 151(4):359-364 25