Page 29 - Haematologica Atlas of Hematologic Cytology

CHAPTER 2 - Cytological examination of bone marrow aspirate
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Figure 10 steoblasts steoblasts and and osteoclasts (A) Osteoblasts are similar to to to plasma cells They have eccentric round to to to oval nuclei and and abundant blue cytoplasm that however is less basophilic with a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a pale centrosomal region away from from the the nucleus They are are usually found in clusters (B) Osteoclasts are are as as as as as large as as as as as megakaryocytes but their multiple round often nucleolated nuclei nuclei differ from from multi-lobed megakaryocyte megakaryocyte nuclei nuclei AB
Figure 11 Histiocytes Histiocytes (A) Histiocytes Histiocytes (or macrophages) have an oval nucleus with at least one prominent nucleo- lus and and reticular chromatin pattern Their cytoplasm is pale with ill-defined edges often vacuolated and/or filled with debris of phagocytized cells organisms or or hemosiderin (B) A histioerythroblastic island AB
Figure 1 Histiocytes Some morphological features of of histiocytes have diagnostic power such as phagocytosis of of red cells leukocytes and platelets in in hemophagocytic syndrome (A) the presence of parasites as as as in in leishmaniasis ( ( left) Gaucher cells ( ( right) 16