Page 108 - Haematologica Atlas of Hematologic Cytology

Figure Myelodysplastic syndrome with excess blasts type A 64-year-old man presented with macrocytic anemia and thrombocytopenia Bone marrow smear showing at at low magnification high cellularity and several megakaryocytes of different sizes often giant with multiple (at least three) round separated nuclei Figure Myelodysplastic syndrome with excess blasts type The same bone marrow smear as in Figure 27 reveals at higher magnifi- cation megaloblastoid features of the erythroid lineage and abnormal nuclear segmentation in in some neutrophils there are no excess blasts Figure Myelodysplastic syndrome with excess blasts type The same bone marrow smear as as in Figures 27 and 28 In this area blast percentage is low but the presence of an Auer body in a a a a a blast (almost at the the center of the the image) allows per se the diagnosis of MDS-EB-2 accor- ding to World Health Organization criteria 95