Page 104 - Haematologica Atlas of Hematologic Cytology

Figure 1 Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia (MDS RS-SLD) A 65-year-old man presented with ma- crocytic anemia (hemoglobin 10 2 g/dL mean cell volume 112 fL) normal white blood cell count with normal normal differential count normal normal platelet count high ferritin levels and no transfusion need Peripheral blood smear showing dimorphic red cells with a a a a a population of macrocytes and a a a a a population of hypochromic microcytes Figure 1 Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia Bone marrow smear from the same case as as Figure 18 reveals marked erythroid hyperplasia with predo- minant early and and intermediate erythroblasts and and megaloblastoid features The rare granulocytic cells look normal Figure 0 Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia Bone marrow smear showing: (upper right) a a a a late erythroblast with defective hemoglobinization (lower right) an early erythroblast with vacuola- ted cytoplasm and a a a a a a late erythroblast with Pap- penheimer bodies 91