Page 128 - 2020_08-Haematologica-web
P. 128

S. von Palffy et al.
naling in hematopoiesis and translational
hematology. Leukemia. 2011;25(9):1379-
1388.
30. Zhang W, Liu HT. MAPK signal pathways in
the regulation of cell proliferation in mam-
malian cells. Cell Res. 2002;12(1):9-18.
31. DiDonato JA, Mercurio F, Karin M. NF- kappaB and the link between inflammation and cancer. Immunol Rev. 2012;246(1):379-
400.
32. Multhoff G, Molls M, Radons J. Chronic
inflammation in cancer development. Front
Immunol. 2011;2:98.
33. Blume-Jensen P, Hunter T. Oncogenic kinase
signalling. Nature. 2001;411(6835):355-365.
34. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;
144(5):646-674.
35. Mirantes C, Passegue E, Pietras EM. Pro-
inflammatory cytokines: emerging players regulating HSC function in normal and dis- eased hematopoiesis. Exp Cell Res. 2014; 329(2):248-254.
36. Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self- reinforcing leukemic niche. Cell Stem Cell. 2013;13(3):285-299.
37. Zhang B, Ho YW, Huang Q, et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myeloge- nous leukemia. Cancer Cell. 2012;21(4):577- 592.
38. Bhatia R, Munthe HA, Williams AD, Zhang F, Forman SJ, Slovak ML. Chronic myeloge- nous leukemia primitive hematopoietic pro- genitors demonstrate increased sensitivity to growth factor-induced proliferation and
maturation. Exp Hematol. 2000;28(12):1401-
1412.
39. Bedi A, Griffin CA, Barber JP, et al. Growth
factor-mediated terminal differentiation of chronic myeloid leukemia. Cancer Res. 1994;54(21):5535-5538.
40. Ohsawa Y, Takayama K, Nishimatsu S, et al. The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy. PLoS One. 2015;10(7):e0133713.
41. Chen JL, Walton KL, Al-Musawi SL, et al. Development of novel activin-targeted ther- apeutics. Mol Ther. 2015;23(3):434-444.
42. Hantschel O, Warsch W, Eckelhart E, et al. BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia. Nat Chem Biol. 2012;8(3):285-293.
2104
haematologica | 2020; 105(8)


































































































   126   127   128   129   130