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Basal NF-κB inhibition impacts BCR responsiveness in CLL
A
B
C
Figure 5. Validation of transcriptional differences of nuclear factor-kB-related genes. (A-C) Real-time quantitative polymerase chain reaction validation of NFKB1, NFKB2 (A), NFKBIB, NFKBID, NFKBIE, BCL3 (B) and TNFAIP3 (C) expres- sion in an extended cohort of unresponsive (n=13) and responsive (n=15) cases of chronic lymphocytic leukemia (CLL). 2-deltaCT values were determined for each sample and individual data plots and the medians are shown. The comparisons between the two groups were done using the Mann-Whitney U-test (*P<0.05, **P<0.01).
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