Page 77 - 2019_09-HaematologicaMondo-web

miR-127 controls HSC maintenance
Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell. 2016;18(2):214-228.
29. Saito Y, Liang G, Egger G, et al. Specific activation of microRNA-127 with down- regulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human can- cer cells. Cancer Cell. 2006;9(6):435-443.
30. Lin SP, Youngson N, Takada S, et al. Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chro- mosome 12. Nat Genet. 2003;35(1):97-102.
31. Zhou Y, Cheunsuchon P, Nakayama Y, et al. Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010; 137(16):2643-2652.
32. Ito M, Sferruzzi-Perri AN, Edwards CA, et al. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Developmen. 2015;142(14):2425-2430.
33. Jiang H, Hua D, Zhang J, et al. MicroRNA- 127-3p promotes glioblastoma cell migra- tion and invasion by targeting the tumor- suppressor gene SEPT7. Oncol Rep. 2014;31(5):2261-2269.
34. Shi L, Wang Y, Lu Z, et al. miR-127 pro- motes EMT and stem-like traits in lung can- cer through a feed-forward regulatory loop.
Oncogene. 2017;36(12):1631-1643.
35. Wang Y, Kong D. Knockdown of lncRNA MEG3 inhibits viability, migration, and invasion and promotes apoptosis by spong- ing miR-127 in osteosarcoma cell. Cell
Biochem. 2018;119(1):669-679.
36. Bi L, Yang Q, Yuan J, et al. MicroRNA-127-
3p acts as a tumor suppressor in epithelial ovarian cancer by regulating the BAG5 gene. Oncol Rep. 2016;36(5):2563-2570.
37. Gao X, Wang X, Cai K, et al. MicroRNA- 127 is a tumor suppressor in human esophageal squamous cell carcinoma through the regulation of oncogene FMNL3. Eur J Pharmacol. 2016;791:603- 610.
38. Herr I, Sahr H, Zhao Z, et al. MiR-127 and miR-376a act as tumor suppressors by in vivo targeting of COA1 and PDIA6 in giant cell tumor of bone. Cancer Lett. 2017;409:49-55.
39. WangD,TangL,WuH,WangK,GuD. MiR-127-3p inhibits cell growth and inva- siveness by targeting ITGA6 in human osteosarcoma. IUBMB Life. 2018;70(5):411- 419.
40. YuY,LiuL,MaR,GongH,XuP,WangC. MicroRNA-127 is aberrantly downregulat- ed and acted as a functional tumor suppres- sor in human pancreatic cancer. Tumor Biol. 2016;37(10):14249-14257.
41. Zhang J, Hou W, Chai M, et al. MicroRNA- 127-3p inhibits proliferation and invasion by targeting SETD8 in human osteosarco- ma cells. Biochem Biophys Res Commun. 2016;469(4):1006-1611.
42. Dixon-McIver A, East P, Mein CA, et al. Distinctive patterns of microRNA expres- sion associated with karyotype in acute myeloid leukaemia. PloS One. 2008; 3(5):e2141.
43. Ma H, Lin Y, Zhao ZA, et al. MicroRNA- 127 Promotes Mesendoderm Differentiation of Mouse Embryonic Stem Cells by Targeting Left-Right Determination Factor 2. J Biol Chem. 2016;291(23):12126-12135.
44. ZhaiL,WuR,HanW,ZhangY,ZhuD. miR-127 enhances myogenic cell differenti- ation by targeting S1PR3. Cell Death Dis. 2017;8(3):e2707.
45. Han YC, Park CY, Bhagat G, et al. microRNA-29a induces aberrant self- renewal capacity in hematopoietic progen- itors, biased myeloid development, and acute myeloid leukemia. J Exp Med. 2010;207(3):475-489.
46. Liu J, Zhang J, Ginzburg Y, et al. Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis. Blood. 2013;121(8):e43-49.
haematologica | 2019; 104(9)
1755