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I. Cortegano et al.
that may provide clues to improve megakaryocyte recon- stitution by using cord blood-derived progenitors for transplantation and for designing better conditions to increase platelet production to treat thrombocytopenic pathologies.
Funding
This work was supported by grants from the Ministerio de Ciencia e Innovación (MICINN SAF2009-12596) and from the Ministerio de Economía y Competitividad (MINECO SAF2012-33916 and SAF2015-70880-R MINECO/FEDER). NS was the recipient of a fellowship from the Centro de Biología
Molecular Severo Ochoa (CBMSO) and IC received a fellow- ship from the MICINN. The CBMSO receives institutional funding from Fundación Ramón Areces. The CNIC is supported by the MEIC and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (MEIC award SEV-2015-0505).
Acknowledgments
The authors would like to thank Miriam Pérez-Crespo and Eduardo Martorell for help with animal care, Fernando Gonzalez for support with the confocal microscopy and Mark Shefton, medical writer from BioMedRed Company, for editing the manuscript.
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