Page 185 - 2019_06-Haematologica-web

High-throughput elucidation of thrombus formation
et al. The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional respons- es and expression. Blood. 2003;101(11): 4372-4379.
19. Watkins NA, O'Connor MN, Rankin A, et al. Definition of novel GPVI polymorphisms and major difference in haplotype frequen- cies between populations by a combination of in-depth exon resequencing and genotyp- ing with tag single nucleotide polymor- phisms. J Thromb Haemost. 2006;4(6):1197- 1205.
20. Petersen R, Lambourne JJ, Javierre BM, et al. Platelet function is modified by common sequence variation in megakaryocyte super enhancers. Nat Commun. 2017;8:16058.
21. Chen L, Kostadima M, Martens JH, et al. Transcriptional diversity during lineage commitment of human blood progenitors.
Science. 2014;345(6204):1251033.
22. De Witt S, Swieringa F, Cosemans JM, Heemskerk JW. Thrombus formation on microspotted arrays of thrombogenic sur- faces. Nat Protocol Exchange. 2014;2014:
3309#.
23. Garner SF, Furnell A, Kahan BC, et al. Platelet
responses to agonists in a cohort of highly characterised platelet donors are consistent over time. Vox Sang. 2017;112(1):18-24.
24. Marx I, Lenting PJ, Adler T, Pendu R, Christophe OD, Denis CV. Correction of bleeding symptoms in von Willebrand fac- tor-deficient mice by liver-expressed von Willebrand factor mutants. Arterioscler Thromb Vasc Biol. 2008;28(3):419-424.
25. Eshel-Green T, Berny MA, Conley RB, McCarty OJ. Effect of sex difference on platelet adhesion, spreading and aggregate formation under flow. Thromb Haemost.
2009;102(5):958-965.
26. Favaloro EJ, Franchini M, Lippi G. Aging
hemostasis: changes to laboratory markers of hemostasis as we age. Semin Thromb Hemost. 2014;40(6):621-633.
27. Jones CI, Bray S, Garner SF, Stephens J, et al. A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood. 2009;114(7):1405-1416.
28. Flamm MH, Colace TV, Chatterjee MS, et al. Multiscale prediction of patient-specific platelet function under flow. Blood. 2012;120(1):190-198.
29. Neeves KB, Onasoga AA, Hansen RR, et al. Sources of variability in platelet accumula- tion on type 1 fibrillar collagen in microflu- idic flow assays. PloS one. 2013;8(1): e54680.
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