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Table of Contents
Volume 104, Issue 2: February 2019
Cover Figure
haematologica Journal of the Ferrata Storti Foundation
Bone marrow smear showing an erythroblastic island in a girl treated with chemotherapy for acute lymphoblastic leukemia. Courtesy of Prof. Rosangela Invernizzi.
Editorials
215 Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia Andrea Bacigalupo
216 Milk and the “Grandmother Effect”– a new contribution to the legacy of Ray Owen William J. Burlingham
219 Another step forward in the 20-year history of IGHV mutations in chronic lymphocytic leukemia Ilaria Del Giudice and Robin Foà
222 The stepchild in myeloma treatments: is allogeneic transplantation not so bad after all? Antonia M.S. Müller et al.
Review Articles
226 CD30-positive primary cutaneous lymphoproliferative disorders: molecular alterations and targeted therapies Lucia Prieto-Torres et al.
236 Pathogenic immune response to therapeutic factor VIII: exacerbated response or failed induction of tolerance? Aditi Varthaman et al.
Articles
Hematopoiesis
245 Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo Xiaomin Wang et al.
Bone Marrow Failure
256 Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia Adrien Contejean et al.
Red Cell Biology & its Disorders
263 Exposure to non-inherited maternal antigens by breastfeeding affects antibody responsiveness Henk Schonewille et al.
Phagocyte Biology & its Disorders
269 Treatment outcomes and prognostic factors in adult patients with secondary hemophagocytic lymphohistiocytosis not associated with malignancy
Jae-Ho Yoon et al.
Acute Myeloid Leukemia
277 Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing Elisabeth K.M. Mack et al.
288 A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia Esther Onecha et al.
Haematologica 2019; vol. 104 no. 2 - February 2019 http://www.haematologica.org/


































































































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