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Impact of the eGVHD App on GvHD assessment
Table 4. Detailed results of participants for graft-versus-host disease (GvHD) vignettes compared to the Expert Gold Standard - GvHD diagnosis.
Results from the "App" group given by 37 participants - n (%)
Expert Gold Standard Diagnosis Classic Late Classic Overlap Missing Other Total
acute acute chronic chronic
ClassicacuteGVHD°° 4 0 2 1 0 74 (5%) (0%) (3%) (1%) (0%) (20%)
LateacuteGVHD°° 5 1 3 0 0 74
Classic chronic GVHD °°°° Overlap chronic GVHD °° Total
(7%) (1%) 3 0
(2%) (0%)
0 0 4
(4%) 3 (2%)
(0%) (0%) (20%) 2 0 148 (1%) (0%) (40%) 0 1 74 (0%) (1%) (20%)
Classic chronic GVHD °°°° Overlap chronic GVHD °° Total
(9%) (20%) 18 9
(11%) (6%)
3 10 51
(4%) (13%) (64%) 104 71 178 (26%) (18%) (44%)
(6%) 23 (14%)
46 (11%)
(0%) (0%) 0 0 (0%) (0%)
(20%) 160 (20%)
67 (91%)
(0%) (0%) (5%)
75 69 145 77 3 1 370
(20%)
(18%) (39%) (21%) (1%) (0%) (100%)
Results from the "No App" group given by 40 participants - n (%)
Late Classic Overlap Missing Other Total
acute chronic chronic
Expert Gold Standard Diagnosis Classic acute
ClassicacuteGVHD°° 0 1 2 1 0 80 (0%) (1%) (3%) (1%) (0%) (20%)
LateacuteGVHD°° 7 16 5 0 0 80
76 (95%)
65 (88%)
140 (95%)
69 (93%)
52 (65%)
110 (69%)
16 (20%)
0 0 80
(0%) (0%) 1 0 (0%) (0%)
(20%) 400 (100%)
n: number; "Missing" corresponds to a lack of answer; "Other" corresponds to any answer not matching the proposed choices.The number of ° symbols used indicates the number of clinical vignettes involved.The highlighted diagonal corresponds to a perfect agreement between participants and expert results.
Figure 2. CONSORT flow diagram. APP: eGVHD App; HCPs: healthcare professionals; HCT: hematopoietic stem cell transplantation. n: number.
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