Page 176 - 2018_09-Mondo

J. Qiao et al.
integrin alpha IIb beta 3. J Biol Chem.
1994;269(46):28859-28864.
6. Suzuki-Inoue K, Hughes CE, Inoue O, et al.
Involvement of Src kinases and PLCgamma2 in clot retraction. Thromb Res. 2007;120(2):251-258.
7. Wonerow P, Pearce AC, Vaux DJ, Watson SP. A critical role for phospholipase Cgamma2 in alphaIIbbeta3-mediated platelet spread- ing. J Biol Chem. 2003;278 (39):37520- 37529.
8. Phillips DR, Jennings LK, Edwards HH. Identification of membrane proteins mediat- ing the interaction of human platelets. J Cell Biol. 1980;86(1):77-86.
9. Shattil SJ, Kashiwagi H, Pampori N. Integrin signaling: the platelet paradigm. Blood. 1998;91(8):2645-2657.
10. Morrell CN, Aggrey AA, Chapman LM, Modjeski KL. Emerging roles for platelets as immune and inflammatory cells. Blood. 2014;123(18):2759-2767.
11. Kapur R, Semple JW. The nonhemostatic immune functions of platelets. Semin Hematol. 2016;53 (Suppl 1):S2-6.
12. Duerschmied D, Bode C, Ahrens I. Immune functions of platelets. Thromb Haemost. 2014;112(4):678-691.
13. Hottz ED, Lopes JF, Freitas C, et al. Platelets mediate increased endothelium permeabil- ity in dengue through NLRP3-inflamma- some activation. Blood. 2013;122(20):3405- 3414.
14. Haneklaus M, O'Neill LA. NLRP3 at the interface of metabolism and inflammation. Immunol Rev. 2015;265(1):53-62.
15. Murthy P, Durco F, Miller-Ocuin JL, et al. The NLRP3 inflammasome and Bruton's
tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation. Biochem Biophys Res Commun. 2017;483(1):230-236.
16. Kovarova M, Hesker PR, Jania L, et al. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J Immunol. 2012;189(4):2006-2016.
17. Qiao J, Wu Y, Liu Y, et al. Busulfan triggers intrinsic mitochondrial-dependent platelet apoptosis independent of platelet activation. Biol Blood Marrow Transplant. 2016;22(9): 1565-1572.
18. QiaoJ,WuY,WuX,etal.Anabsenceof platelet activation following thalidomide treatment in vitro or in vivo. Oncotarget. 2017;8(22):35776-35782.
19. Qiao J, Liu Y, Li D, et al. Imbalanced expres- sion of Bcl-xL and Bax in platelets treated with plasma from immune thrombocytope- nia. Immunol Res. 2016;64(2):604-609.
20. Qiao J, Huang Y, Xia Y, et al. Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation. Sci Rep. 2015;5:17828.
21. Rivera J, Lozano ML, Navarro-Nunez L, Vicente V. Platelet receptors and signaling in the dynamics of thrombus formation. Haematologica. 2009;94(5):700-711.
22. Swieringa F, Kuijpers MJ, Heemskerk JW, van der Meijden PE. Targeting platelet recep- tor function in thrombus formation: the risk of bleeding. Blood Rev. 2014;28(1):9-21.
23. Pagel O, Walter E, Jurk K, Zahedi RP. Taking the stock of granule cargo: platelet releasate proteomics. Platelets. 2017;28(2):119-128.
24. Jonnalagadda D, Izu LT, Whiteheart SW.
Platelet secretion is kinetically heteroge- neous in an agonist-responsive manner. Blood. 2012;120(26):5209-5216.
25. Italiano JE, Richardson JL, Patel-Hett S, et al. Angiogenesis is regulated by a novel mecha- nism: pro- and antiangiogenic proteins are organized into separate platelet alpha gran- ules and differentially released. Blood. 2008;111(3):1227-1233.
26. Flevaris P, Stojanovic A, Gong H, Chishti A, Welch E, Du X. A molecular switch that controls cell spreading and retraction. J Cell Biol. 2007;179(3):553-565.
27. Davis BK, Wen H, Ting JP. The inflamma- some NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol. 2011;29:707-735.
28. Denis MM, Tolley ND, Bunting M, et al. Escaping the nuclear confines: signal-depen- dent pre-mRNA splicing in anucleate platelets. Cell. 2005;122(3):379-391.
29. Beaulieu LM, Lin E, Mick E, et al. Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arterioscler Thromb Vasc Biol. 2014;34(3): 552-564.
30. Jiang H, He H, Chen Y, et al. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 2017;214(11):3219-3238.
31. Aksu K, Donmez A, Keser G. Inflammation- induced thrombosis: mechanisms, disease associations and management. Curr Pharm Des. 2012;18(11):1478-1493.
32. Esmon CT. Inflammation and thrombosis. J Thromb Haemost. 2003;1(7):1343-1348.
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