Page 267 - Haematologica Vol. 109 - July 2024

LETTER TO THE EDITOR
Figure 2. Exposure-adjusted incidence rates of select adverse events of special interest over time. Adverse events of special interest (AESI) are grouped terms as defined in the legend for Figure 1. Exposure-adjusted incidence rates (EAIR) at each time interval were calculated as the number of patients who experienced a specific AESI during that time interval divided by the total exposure time in years at the corresponding time interval. This value was then multiplied by 100 to express as persons per 100 person-years (PY). Data are shown for the total pooled zanubrutinib population (N=1,550) and the comparative analysis patient populations (patients treated with zanubrutinib [N=425] or ibrutinib [N=422] as part of the randomized studies ASPEN cohort 1 or ALPINE; each treatment group is labeled as ASPEN/ALPINE).
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