Page 185 - Haematologica June

Presentation of ADAMTS13 peptides on HLA-DR and HLA-DQ
Table 2. HLA-DRB1 and HLA-DQA1/DQB1 peptide presentation and core-peptide binding affinity prediction. The ADAMTS13-derived peptides identified for each donor were analyzed for their binding affinities to the donor specific HLA-DRB1 (A) or HLA-DQA1/HLA-DQB1 alleles (B) using the NetMHCIIpan 3.1 software. The affinity value is presented in nM. For each peptide, a binding core was predicted. Binding cores with the high- est affinity to the particular MHC-II are shown in yellow. Right panel represents the domain origin of each peptide.
A
haematologica | 2018; 103(6)
1087